To learn more see below:
https://www.elsevier.com/books/the-exposome/miller/978-0-12-814079-6
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- The U.S. version of the #exposome wikipedia site has returned after a multi-year absence. https://t.co/TsZSr75bU3
Exposome-Related News
- Environmental Factor - April 2022: "All of Us" Research Program a boon to personalized health, biomedicine - Environmental Factor Newsletter
- June 2022: Future research priorities: precision health and predictive tox - Environmental Factor Newsletter
- AI, epigenetics hot topics at advisory council meeting - Environmental Factor Newsletter
- An exposome atlas of serum reveals the risk of chronic diseases in the Chinese population - Nature.com
- Uncovering the Surge in Early-Onset Bowel Cancer: A Multi-Continent, £20 Million Research Venture - Medriva
- LinusBio Named “Fierce 15” Company of 2023 by Fierce Medtech - Business Wire
- March 2024: NIEHS catalyzes research collaborations in India - Environmental Factor Newsletter
- Environmental Factor - March 2024: Epigenomics and epitranscriptomics front and center at Council - Environmental Factor Newsletter
- International Pooled Analysis of Leisure-time Physical Activity and Premenopausal Breast Cancer in Women From 19 Cohorts
- Automated, High-throughput Quantification of EGFP-expressing Neutrophils in Zebrafish by Machine Learning and a Highly-parallelized Microscope
- Gut microbial ecology and exposome of a healthy Pakistani cohort - springermedizin.de
- Highly accurate diagnosis of pancreatic cancer by integrative modeling using gut microbiome and exposome data - ScienceDirect.com
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Definition
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
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Vision
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
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Need
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.